Aspartate aminotransferase increased: Which Medications Cause It? (29,189 Reports Across 1,193 Drugs)
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Aspartate aminotransferase increased has been reported as an adverse event with 1,193 different drugs in the FDA's FAERS database, with 29,189 total reports. 2,885 of these reports resulted in death.The drugs most commonly associated with Aspartate aminotransferase increased are METHOTREXATE, RITUXIMAB, and ADALIMUMAB.
29,189
Total Reports
1,193
Drugs Involved
2,885
Deaths
11,419
Hospitalizations
51.5 yrs
Average Patient Age
55.5% / 44.5%
Female / Male
Which Drugs Cause Aspartate aminotransferase increased Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| METHOTREXATE | 1,600 | 0.6% | 77 | 895 | 63 |
| RITUXIMAB | 1,351 | 0.8% | 105 | 738 | 57 |
| ADALIMUMAB | 1,166 | 0.2% | 33 | 733 | 35 |
| TOCILIZUMAB | 975 | 1.0% | 24 | 651 | 37 |
| ETANERCEPT | 939 | 0.3% | 5 | 588 | 35 |
| ACETAMINOPHEN | 865 | 0.6% | 131 | 620 | 165 |
| LEFLUNOMIDE | 863 | 1.5% | 1 | 603 | 24 |
| INFLIXIMAB | 823 | 0.6% | 11 | 589 | 28 |
| ABATACEPT | 778 | 0.7% | 1 | 597 | 23 |
| NIVOLUMAB | 758 | 0.9% | 181 | 491 | 98 |
| RIBOCICLIB | 745 | 2.7% | 88 | 209 | 118 |
| HYDROXYCHLOROQUINE | 739 | 1.1% | 19 | 567 | 28 |
| REMDESIVIR | 713 | 6.8% | 55 | 102 | 23 |
| SULFASALAZINE | 681 | 1.7% | 0 | 553 | 20 |
| CYCLOPHOSPHAMIDE | 675 | 0.5% | 100 | 218 | 45 |
| BEVACIZUMAB | 672 | 0.9% | 98 | 180 | 33 |
| PEMBROLIZUMAB | 655 | 0.8% | 89 | 310 | 35 |
| PACLITAXEL | 634 | 0.8% | 117 | 259 | 31 |
| PREDNISONE | 595 | 0.4% | 70 | 201 | 42 |
| FINGOLIMOD | 582 | 0.8% | 9 | 108 | 20 |