Does APREMILAST Cause Bone erosion? 700 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 700 reports of Bone erosion have been filed in association with APREMILAST (Otezla). This represents 0.5% of all adverse event reports for APREMILAST.
700
Reports of Bone erosion with APREMILAST
0.5%
of all APREMILAST reports
427
Deaths
319
Hospitalizations
How Dangerous Is Bone erosion From APREMILAST?
Of the 700 reports, 427 (61.0%) resulted in death, 319 (45.6%) required hospitalization, and 319 (45.6%) were considered life-threatening.
Is Bone erosion Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for APREMILAST. However, 700 reports have been filed with the FAERS database.
What Other Side Effects Does APREMILAST Cause?
Diarrhoea (23,752)
Nausea (21,352)
Psoriasis (19,255)
Headache (17,024)
Drug ineffective (14,121)
Abdominal discomfort (7,653)
Psoriatic arthropathy (7,035)
Vomiting (5,959)
Rash (5,883)
Pain (5,676)
What Other Drugs Cause Bone erosion?
METHOTREXATE (1,713)
ADALIMUMAB (1,640)
ETANERCEPT (1,474)
TOCILIZUMAB (1,374)
LEFLUNOMIDE (1,291)
ABATACEPT (1,264)
HYDROXYCHLOROQUINE (1,138)
RITUXIMAB (1,064)
SULFASALAZINE (1,042)
INFLIXIMAB (1,040)
Which APREMILAST Alternatives Have Lower Bone erosion Risk?
APREMILAST vs APREPITANT
APREMILAST vs APROTININ
APREMILAST vs ARANESP
APREMILAST vs ARAVA
APREMILAST vs AREDIA