Bone erosion: Which Medications Cause It? (2,883 Reports Across 292 Drugs)
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Bone erosion has been reported as an adverse event with 292 different drugs in the FDA's FAERS database, with 2,883 total reports. 704 of these reports resulted in death.The drugs most commonly associated with Bone erosion are METHOTREXATE, ADALIMUMAB, and ETANERCEPT.
2,883
Total Reports
292
Drugs Involved
704
Deaths
862
Hospitalizations
53.3 yrs
Average Patient Age
78.0% / 22.0%
Female / Male
Which Drugs Cause Bone erosion Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| METHOTREXATE | 1,713 | 0.7% | 495 | 467 | 396 |
| ADALIMUMAB | 1,640 | 0.3% | 532 | 523 | 412 |
| ETANERCEPT | 1,474 | 0.4% | 413 | 389 | 323 |
| TOCILIZUMAB | 1,374 | 1.4% | 507 | 436 | 373 |
| LEFLUNOMIDE | 1,291 | 2.3% | 405 | 446 | 383 |
| ABATACEPT | 1,264 | 1.1% | 452 | 420 | 381 |
| HYDROXYCHLOROQUINE | 1,138 | 1.7% | 453 | 408 | 347 |
| RITUXIMAB | 1,064 | 0.6% | 455 | 461 | 391 |
| SULFASALAZINE | 1,042 | 2.6% | 462 | 413 | 369 |
| INFLIXIMAB | 1,040 | 0.7% | 453 | 392 | 352 |
| CERTOLIZUMAB PEGOL | 896 | 0.9% | 471 | 397 | 365 |
| GOLIMUMAB | 880 | 1.3% | 432 | 359 | 326 |
| TOFACITINIB | 810 | 0.5% | 357 | 309 | 299 |
| AZATHIOPRINE | 721 | 2.2% | 336 | 240 | 231 |
| APREMILAST | 700 | 0.5% | 427 | 319 | 319 |
| PREDNISONE | 651 | 0.4% | 445 | 408 | 371 |
| USTEKINUMAB | 648 | 0.8% | 399 | 321 | 314 |
| DICLOFENAC | 638 | 0.7% | 540 | 435 | 426 |
| FOLIC ACID | 610 | 2.7% | 453 | 354 | 347 |
| ALENDRONATE | 604 | 2.2% | 469 | 383 | 369 |