Does DICLOFENAC Cause Bone erosion? 638 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 638 reports of Bone erosion have been filed in association with DICLOFENAC (Diclofenac Sodium Delayed Release). This represents 0.7% of all adverse event reports for DICLOFENAC.
638
Reports of Bone erosion with DICLOFENAC
0.7%
of all DICLOFENAC reports
540
Deaths
435
Hospitalizations
How Dangerous Is Bone erosion From DICLOFENAC?
Of the 638 reports, 540 (84.6%) resulted in death, 435 (68.2%) required hospitalization, and 426 (66.8%) were considered life-threatening.
Is Bone erosion Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DICLOFENAC. However, 638 reports have been filed with the FAERS database.
What Other Side Effects Does DICLOFENAC Cause?
Drug ineffective (24,885)
Product use in unapproved indication (12,197)
Off label use (10,370)
Pain (9,276)
Product use issue (8,009)
Fatigue (7,908)
Rash (7,852)
Rheumatoid arthritis (7,366)
Abdominal discomfort (7,257)
Product administered at inappropriate site (6,919)
What Other Drugs Cause Bone erosion?
METHOTREXATE (1,713)
ADALIMUMAB (1,640)
ETANERCEPT (1,474)
TOCILIZUMAB (1,374)
LEFLUNOMIDE (1,291)
ABATACEPT (1,264)
HYDROXYCHLOROQUINE (1,138)
RITUXIMAB (1,064)
SULFASALAZINE (1,042)
INFLIXIMAB (1,040)
Which DICLOFENAC Alternatives Have Lower Bone erosion Risk?
DICLOFENAC vs DICLOFENAC DIETHYLAMINE
DICLOFENAC vs DICLOFENAC EPOLAMINE
DICLOFENAC vs DICLOFENAC\DICLOFENAC
DICLOFENAC vs DICLOFENAC\MISOPROSTOL
DICLOFENAC vs DICLOXACILLIN