Does APREMILAST Cause Cardiac failure? 108 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 108 reports of Cardiac failure have been filed in association with APREMILAST (Otezla). This represents 0.1% of all adverse event reports for APREMILAST.
108
Reports of Cardiac failure with APREMILAST
0.1%
of all APREMILAST reports
21
Deaths
46
Hospitalizations
How Dangerous Is Cardiac failure From APREMILAST?
Of the 108 reports, 21 (19.4%) resulted in death, 46 (42.6%) required hospitalization, and 4 (3.7%) were considered life-threatening.
Is Cardiac failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for APREMILAST. However, 108 reports have been filed with the FAERS database.
What Other Side Effects Does APREMILAST Cause?
Diarrhoea (23,752)
Nausea (21,352)
Psoriasis (19,255)
Headache (17,024)
Drug ineffective (14,121)
Abdominal discomfort (7,653)
Psoriatic arthropathy (7,035)
Vomiting (5,959)
Rash (5,883)
Pain (5,676)
What Other Drugs Cause Cardiac failure?
SACUBITRIL\VALSARTAN (4,504)
FUROSEMIDE (1,841)
APIXABAN (1,575)
CYCLOPHOSPHAMIDE (1,514)
DOXORUBICIN (1,367)
ADALIMUMAB (1,278)
DEXAMETHASONE (1,271)
TREPROSTINIL (1,168)
BISOPROLOL (1,159)
LENALIDOMIDE (1,115)
Which APREMILAST Alternatives Have Lower Cardiac failure Risk?
APREMILAST vs APREPITANT
APREMILAST vs APROTININ
APREMILAST vs ARANESP
APREMILAST vs ARAVA
APREMILAST vs AREDIA