Does APREMILAST Cause Hepatic enzyme increased? 2,127 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 2,127 reports of Hepatic enzyme increased have been filed in association with APREMILAST (Otezla). This represents 1.6% of all adverse event reports for APREMILAST.
2,127
Reports of Hepatic enzyme increased with APREMILAST
1.6%
of all APREMILAST reports
1,516
Deaths
1,459
Hospitalizations
How Dangerous Is Hepatic enzyme increased From APREMILAST?
Of the 2,127 reports, 1,516 (71.3%) resulted in death, 1,459 (68.6%) required hospitalization, and 1,402 (65.9%) were considered life-threatening.
Is Hepatic enzyme increased Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for APREMILAST. However, 2,127 reports have been filed with the FAERS database.
What Other Side Effects Does APREMILAST Cause?
Diarrhoea (23,752)
Nausea (21,352)
Psoriasis (19,255)
Headache (17,024)
Drug ineffective (14,121)
Abdominal discomfort (7,653)
Psoriatic arthropathy (7,035)
Vomiting (5,959)
Rash (5,883)
Pain (5,676)
What Other Drugs Cause Hepatic enzyme increased?
METHOTREXATE (9,857)
ADALIMUMAB (8,693)
TOCILIZUMAB (7,691)
ETANERCEPT (7,481)
ABATACEPT (7,397)
RITUXIMAB (7,247)
LEFLUNOMIDE (7,173)
INFLIXIMAB (6,778)
HYDROXYCHLOROQUINE (6,555)
TOFACITINIB (6,269)
Which APREMILAST Alternatives Have Lower Hepatic enzyme increased Risk?
APREMILAST vs APREPITANT
APREMILAST vs APROTININ
APREMILAST vs ARANESP
APREMILAST vs ARAVA
APREMILAST vs AREDIA