Does APREMILAST Cause Herpes zoster? 322 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 322 reports of Herpes zoster have been filed in association with APREMILAST (Otezla). This represents 0.2% of all adverse event reports for APREMILAST.
322
Reports of Herpes zoster with APREMILAST
0.2%
of all APREMILAST reports
7
Deaths
83
Hospitalizations
How Dangerous Is Herpes zoster From APREMILAST?
Of the 322 reports, 7 (2.2%) resulted in death, 83 (25.8%) required hospitalization, and 6 (1.9%) were considered life-threatening.
Is Herpes zoster Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for APREMILAST. However, 322 reports have been filed with the FAERS database.
What Other Side Effects Does APREMILAST Cause?
Diarrhoea (23,752)
Nausea (21,352)
Psoriasis (19,255)
Headache (17,024)
Drug ineffective (14,121)
Abdominal discomfort (7,653)
Psoriatic arthropathy (7,035)
Vomiting (5,959)
Rash (5,883)
Pain (5,676)
What Other Drugs Cause Herpes zoster?
ADALIMUMAB (3,783)
TOFACITINIB (3,575)
ETANERCEPT (3,129)
METHOTREXATE (2,589)
RITUXIMAB (2,228)
INFLIXIMAB (2,081)
LENALIDOMIDE (1,762)
TOCILIZUMAB (1,676)
OCRELIZUMAB (1,433)
ABATACEPT (1,395)
Which APREMILAST Alternatives Have Lower Herpes zoster Risk?
APREMILAST vs APREPITANT
APREMILAST vs APROTININ
APREMILAST vs ARANESP
APREMILAST vs ARAVA
APREMILAST vs AREDIA