Does METHOTREXATE Cause Herpes zoster? 2,589 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 2,589 reports of Herpes zoster have been filed in association with METHOTREXATE (Methotrexate). This represents 1.0% of all adverse event reports for METHOTREXATE.
2,589
Reports of Herpes zoster with METHOTREXATE
1.0%
of all METHOTREXATE reports
128
Deaths
694
Hospitalizations
How Dangerous Is Herpes zoster From METHOTREXATE?
Of the 2,589 reports, 128 (4.9%) resulted in death, 694 (26.8%) required hospitalization, and 146 (5.6%) were considered life-threatening.
Is Herpes zoster Listed in the Official Label?
Yes, Herpes zoster is listed as a known adverse reaction in the official FDA drug label for METHOTREXATE.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Herpes zoster?
ADALIMUMAB (3,783)
TOFACITINIB (3,575)
ETANERCEPT (3,129)
RITUXIMAB (2,228)
INFLIXIMAB (2,081)
LENALIDOMIDE (1,762)
TOCILIZUMAB (1,676)
OCRELIZUMAB (1,433)
ABATACEPT (1,395)
PREDNISONE (1,362)
Which METHOTREXATE Alternatives Have Lower Herpes zoster Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA