Does APREMILAST Cause Hypertension? 2,472 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 2,472 reports of Hypertension have been filed in association with APREMILAST (Otezla). This represents 1.8% of all adverse event reports for APREMILAST.
2,472
Reports of Hypertension with APREMILAST
1.8%
of all APREMILAST reports
1,556
Deaths
1,514
Hospitalizations
How Dangerous Is Hypertension From APREMILAST?
Of the 2,472 reports, 1,556 (62.9%) resulted in death, 1,514 (61.2%) required hospitalization, and 1,394 (56.4%) were considered life-threatening.
Is Hypertension Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for APREMILAST. However, 2,472 reports have been filed with the FAERS database.
What Other Side Effects Does APREMILAST Cause?
Diarrhoea (23,752)
Nausea (21,352)
Psoriasis (19,255)
Headache (17,024)
Drug ineffective (14,121)
Abdominal discomfort (7,653)
Psoriatic arthropathy (7,035)
Vomiting (5,959)
Rash (5,883)
Pain (5,676)
What Other Drugs Cause Hypertension?
ADALIMUMAB (9,032)
METHOTREXATE (7,143)
RITUXIMAB (6,760)
PREDNISONE (6,087)
INFLIXIMAB (5,874)
ETANERCEPT (5,677)
TOCILIZUMAB (5,492)
ABATACEPT (5,114)
TOFACITINIB (4,991)
ALENDRONATE (4,373)
Which APREMILAST Alternatives Have Lower Hypertension Risk?
APREMILAST vs APREPITANT
APREMILAST vs APROTININ
APREMILAST vs ARANESP
APREMILAST vs ARAVA
APREMILAST vs AREDIA