Does METHOTREXATE Cause Hypertension? 7,143 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 7,143 reports of Hypertension have been filed in association with METHOTREXATE (Methotrexate). This represents 2.8% of all adverse event reports for METHOTREXATE.
7,143
Reports of Hypertension with METHOTREXATE
2.8%
of all METHOTREXATE reports
1,923
Deaths
3,128
Hospitalizations
How Dangerous Is Hypertension From METHOTREXATE?
Of the 7,143 reports, 1,923 (26.9%) resulted in death, 3,128 (43.8%) required hospitalization, and 1,981 (27.7%) were considered life-threatening.
Is Hypertension Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 7,143 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Hypertension?
ADALIMUMAB (9,032)
RITUXIMAB (6,760)
PREDNISONE (6,087)
INFLIXIMAB (5,874)
ETANERCEPT (5,677)
TOCILIZUMAB (5,492)
ABATACEPT (5,114)
TOFACITINIB (4,991)
ALENDRONATE (4,373)
LEFLUNOMIDE (4,351)
Which METHOTREXATE Alternatives Have Lower Hypertension Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA