Does APREMILAST Cause Immunodeficiency? 75 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 75 reports of Immunodeficiency have been filed in association with APREMILAST (Otezla). This represents 0.1% of all adverse event reports for APREMILAST.
75
Reports of Immunodeficiency with APREMILAST
0.1%
of all APREMILAST reports
16
Deaths
36
Hospitalizations
How Dangerous Is Immunodeficiency From APREMILAST?
Of the 75 reports, 16 (21.3%) resulted in death, 36 (48.0%) required hospitalization, and 23 (30.7%) were considered life-threatening.
Is Immunodeficiency Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for APREMILAST. However, 75 reports have been filed with the FAERS database.
What Other Side Effects Does APREMILAST Cause?
Diarrhoea (23,752)
Nausea (21,352)
Psoriasis (19,255)
Headache (17,024)
Drug ineffective (14,121)
Abdominal discomfort (7,653)
Psoriatic arthropathy (7,035)
Vomiting (5,959)
Rash (5,883)
Pain (5,676)
What Other Drugs Cause Immunodeficiency?
ADALIMUMAB (2,981)
RITUXIMAB (1,256)
TOCILIZUMAB (1,061)
ABATACEPT (1,042)
METHOTREXATE (926)
ETANERCEPT (799)
INFLIXIMAB (693)
CETIRIZINE (650)
METHYLPREDNISOLONE (615)
ALBUTEROL (599)
Which APREMILAST Alternatives Have Lower Immunodeficiency Risk?
APREMILAST vs APREPITANT
APREMILAST vs APROTININ
APREMILAST vs ARANESP
APREMILAST vs ARAVA
APREMILAST vs AREDIA