Does METHOTREXATE Cause Immunodeficiency? 926 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 926 reports of Immunodeficiency have been filed in association with METHOTREXATE (Methotrexate). This represents 0.4% of all adverse event reports for METHOTREXATE.
926
Reports of Immunodeficiency with METHOTREXATE
0.4%
of all METHOTREXATE reports
77
Deaths
496
Hospitalizations
How Dangerous Is Immunodeficiency From METHOTREXATE?
Of the 926 reports, 77 (8.3%) resulted in death, 496 (53.6%) required hospitalization, and 127 (13.7%) were considered life-threatening.
Is Immunodeficiency Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 926 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Immunodeficiency?
ADALIMUMAB (2,981)
RITUXIMAB (1,256)
TOCILIZUMAB (1,061)
ABATACEPT (1,042)
ETANERCEPT (799)
INFLIXIMAB (693)
CETIRIZINE (650)
METHYLPREDNISOLONE (615)
ALBUTEROL (599)
PREDNISONE (576)
Which METHOTREXATE Alternatives Have Lower Immunodeficiency Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA