Does APREMILAST Cause Irritability? 288 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 288 reports of Irritability have been filed in association with APREMILAST (Otezla). This represents 0.2% of all adverse event reports for APREMILAST.
288
Reports of Irritability with APREMILAST
0.2%
of all APREMILAST reports
0
Deaths
5
Hospitalizations
How Dangerous Is Irritability From APREMILAST?
Of the 288 reports, 5 (1.7%) required hospitalization, and 2 (0.7%) were considered life-threatening.
Is Irritability Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for APREMILAST. However, 288 reports have been filed with the FAERS database.
What Other Side Effects Does APREMILAST Cause?
Diarrhoea (23,752)
Nausea (21,352)
Psoriasis (19,255)
Headache (17,024)
Drug ineffective (14,121)
Abdominal discomfort (7,653)
Psoriatic arthropathy (7,035)
Vomiting (5,959)
Rash (5,883)
Pain (5,676)
What Other Drugs Cause Irritability?
DULOXETINE (3,554)
LEVOTHYROXINE (1,692)
LEVETIRACETAM (1,067)
ARIPIPRAZOLE (851)
LEVONORGESTREL (796)
RIBAVIRIN (775)
AMPHETAMINE ASPARTATE\AMPHETAMINE\DEXTROAMPHETAMINE SACCHARATE\DEXTROAMPHETAMINE (745)
PREGABALIN (736)
METHYLPHENIDATE (735)
QUETIAPINE (638)
Which APREMILAST Alternatives Have Lower Irritability Risk?
APREMILAST vs APREPITANT
APREMILAST vs APROTININ
APREMILAST vs ARANESP
APREMILAST vs ARAVA
APREMILAST vs AREDIA