Does APREMILAST Cause Nephrolithiasis? 317 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 317 reports of Nephrolithiasis have been filed in association with APREMILAST (Otezla). This represents 0.2% of all adverse event reports for APREMILAST.
317
Reports of Nephrolithiasis with APREMILAST
0.2%
of all APREMILAST reports
0
Deaths
105
Hospitalizations
How Dangerous Is Nephrolithiasis From APREMILAST?
Of the 317 reports, 105 (33.1%) required hospitalization, and 1 (0.3%) were considered life-threatening.
Is Nephrolithiasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for APREMILAST. However, 317 reports have been filed with the FAERS database.
What Other Side Effects Does APREMILAST Cause?
Diarrhoea (23,752)
Nausea (21,352)
Psoriasis (19,255)
Headache (17,024)
Drug ineffective (14,121)
Abdominal discomfort (7,653)
Psoriatic arthropathy (7,035)
Vomiting (5,959)
Rash (5,883)
Pain (5,676)
What Other Drugs Cause Nephrolithiasis?
ADALIMUMAB (2,416)
ETANERCEPT (1,292)
INFLIXIMAB (981)
METHOTREXATE (979)
ABATACEPT (788)
TOPIRAMATE (768)
CERTOLIZUMAB PEGOL (735)
RITUXIMAB (709)
TOFACITINIB (699)
SODIUM OXYBATE (698)
Which APREMILAST Alternatives Have Lower Nephrolithiasis Risk?
APREMILAST vs APREPITANT
APREMILAST vs APROTININ
APREMILAST vs ARANESP
APREMILAST vs ARAVA
APREMILAST vs AREDIA