Does APREMILAST Cause Sciatica? 979 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 979 reports of Sciatica have been filed in association with APREMILAST (Otezla). This represents 0.7% of all adverse event reports for APREMILAST.
979
Reports of Sciatica with APREMILAST
0.7%
of all APREMILAST reports
795
Deaths
760
Hospitalizations
How Dangerous Is Sciatica From APREMILAST?
Of the 979 reports, 795 (81.2%) resulted in death, 760 (77.6%) required hospitalization, and 764 (78.0%) were considered life-threatening.
Is Sciatica Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for APREMILAST. However, 979 reports have been filed with the FAERS database.
What Other Side Effects Does APREMILAST Cause?
Diarrhoea (23,752)
Nausea (21,352)
Psoriasis (19,255)
Headache (17,024)
Drug ineffective (14,121)
Abdominal discomfort (7,653)
Psoriatic arthropathy (7,035)
Vomiting (5,959)
Rash (5,883)
Pain (5,676)
What Other Drugs Cause Sciatica?
ADALIMUMAB (2,253)
METHOTREXATE (1,745)
TOCILIZUMAB (1,681)
RITUXIMAB (1,671)
ABATACEPT (1,621)
ETANERCEPT (1,583)
INFLIXIMAB (1,449)
HYDROXYCHLOROQUINE (1,430)
PREGABALIN (1,411)
LEFLUNOMIDE (1,394)
Which APREMILAST Alternatives Have Lower Sciatica Risk?
APREMILAST vs APREPITANT
APREMILAST vs APROTININ
APREMILAST vs ARANESP
APREMILAST vs ARAVA
APREMILAST vs AREDIA