Does METHOTREXATE Cause Sciatica? 1,745 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,745 reports of Sciatica have been filed in association with METHOTREXATE (Methotrexate). This represents 0.7% of all adverse event reports for METHOTREXATE.
1,745
Reports of Sciatica with METHOTREXATE
0.7%
of all METHOTREXATE reports
911
Deaths
970
Hospitalizations
How Dangerous Is Sciatica From METHOTREXATE?
Of the 1,745 reports, 911 (52.2%) resulted in death, 970 (55.6%) required hospitalization, and 924 (53.0%) were considered life-threatening.
Is Sciatica Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 1,745 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Sciatica?
ADALIMUMAB (2,253)
TOCILIZUMAB (1,681)
RITUXIMAB (1,671)
ABATACEPT (1,621)
ETANERCEPT (1,583)
INFLIXIMAB (1,449)
HYDROXYCHLOROQUINE (1,430)
PREGABALIN (1,411)
LEFLUNOMIDE (1,394)
SULFASALAZINE (1,362)
Which METHOTREXATE Alternatives Have Lower Sciatica Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA