ASFOTASE ALFA for Off label use: Side Effects & Safety Data
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There are 20 adverse event reports in the FDA FAERS database where ASFOTASE ALFA was used for Off label use.
Most Reported Side Effects for ASFOTASE ALFA
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Injection site pain | 1,227 | 14.0% | 0 | 22 |
| Injection site erythema | 828 | 9.5% | 0 | 22 |
| Fatigue | 759 | 8.7% | 0 | 36 |
| Pain | 673 | 7.7% | 1 | 44 |
| Injection site reaction | 659 | 7.5% | 0 | 12 |
| Arthralgia | 524 | 6.0% | 0 | 29 |
| Injection site bruising | 469 | 5.4% | 0 | 6 |
| Pain in extremity | 463 | 5.3% | 0 | 19 |
| Injection site swelling | 417 | 4.8% | 0 | 9 |
| Headache | 322 | 3.7% | 0 | 26 |
| Injection site pruritus | 317 | 3.6% | 0 | 9 |
| Blood alkaline phosphatase increased | 283 | 3.2% | 3 | 29 |
| Injection site mass | 281 | 3.2% | 0 | 9 |
| Nausea | 264 | 3.0% | 0 | 22 |
| Malaise | 260 | 3.0% | 0 | 12 |
Other Indications for ASFOTASE ALFA
Hypophosphatasia (4,205)
Product used for unknown indication (3,953)
Phosphorus metabolism disorder (232)
Hypophosphataemia (29)
Other Drugs Used for Off label use
LENALIDOMIDE (5,767)
ECULIZUMAB (3,550)
CERTOLIZUMAB PEGOL (2,256)
ABOBOTULINUMTOXINA (2,170)
LEVETIRACETAM (2,161)
APREMILAST (1,995)
PROPRANOLOL (1,576)
CETIRIZINE (1,416)
HUMAN IMMUNOGLOBULIN G (1,129)
THALIDOMIDE (1,033)