Does BENZOCAINE Cause Pemphigus? 22 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 22 reports of Pemphigus have been filed in association with BENZOCAINE (ANAL-ESE). This represents 4.0% of all adverse event reports for BENZOCAINE.
22
Reports of Pemphigus with BENZOCAINE
4.0%
of all BENZOCAINE reports
12
Deaths
22
Hospitalizations
How Dangerous Is Pemphigus From BENZOCAINE?
Of the 22 reports, 12 (54.5%) resulted in death, 22 (100.0%) required hospitalization, and 22 (100.0%) were considered life-threatening.
Is Pemphigus Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BENZOCAINE. However, 22 reports have been filed with the FAERS database.
What Other Side Effects Does BENZOCAINE Cause?
Methaemoglobinaemia (162)
Drug hypersensitivity (57)
Dyspnoea (53)
Off label use (53)
Drug ineffective (49)
Condition aggravated (37)
Maternal exposure during pregnancy (36)
Asthma (32)
Cyanosis (32)
Asthenia (30)
What Other Drugs Cause Pemphigus?
RITUXIMAB (8,574)
ABATACEPT (8,441)
METHOTREXATE (8,414)
PREDNISONE (8,260)
LEFLUNOMIDE (8,252)
TOCILIZUMAB (8,210)
FOLIC ACID (8,128)
ADALIMUMAB (8,079)
CETIRIZINE (8,063)
HYDROXYCHLOROQUINE (8,051)
Which BENZOCAINE Alternatives Have Lower Pemphigus Risk?
BENZOCAINE vs BENZODIAZEPINE
BENZOCAINE vs BENZONATATE
BENZOCAINE vs BENZOYL PEROXIDE
BENZOCAINE vs BENZOYL PEROXIDE\CLINDAMYCIN
BENZOCAINE vs BENZOYLECGONINE