Does BUPIVACAINE Cause Arthropathy? 25 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 25 reports of Arthropathy have been filed in association with BUPIVACAINE (Bupivacaine Hydrochloride). This represents 0.2% of all adverse event reports for BUPIVACAINE.
25
Reports of Arthropathy with BUPIVACAINE
0.2%
of all BUPIVACAINE reports
13
Deaths
14
Hospitalizations
How Dangerous Is Arthropathy From BUPIVACAINE?
Of the 25 reports, 13 (52.0%) resulted in death, 14 (56.0%) required hospitalization, and 13 (52.0%) were considered life-threatening.
Is Arthropathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BUPIVACAINE. However, 25 reports have been filed with the FAERS database.
What Other Side Effects Does BUPIVACAINE Cause?
Drug ineffective (3,068)
Off label use (912)
Pain (746)
Anaesthetic complication (585)
Maternal exposure during pregnancy (491)
Hypotension (460)
Hypoaesthesia (455)
Exposure during pregnancy (391)
Nausea (328)
Drug withdrawal syndrome (280)
What Other Drugs Cause Arthropathy?
ETANERCEPT (11,842)
ADALIMUMAB (11,670)
ABATACEPT (11,099)
METHOTREXATE (10,973)
TOCILIZUMAB (9,816)
LEFLUNOMIDE (9,277)
HYDROXYCHLOROQUINE (8,770)
RITUXIMAB (8,619)
INFLIXIMAB (8,410)
SULFASALAZINE (7,545)
Which BUPIVACAINE Alternatives Have Lower Arthropathy Risk?
BUPIVACAINE vs BUPIVACAINE\BUPIVACAINE ANHYDROUS
BUPIVACAINE vs BUPIVACAINE\EPINEPHRINE
BUPIVACAINE vs BUPIVACAINE\MELOXICAM
BUPIVACAINE vs BUPRENORPHINE
BUPIVACAINE vs BUPRENORPHINE\NALOXONE