Does METHOTREXATE Cause Arthropathy? 10,973 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 10,973 reports of Arthropathy have been filed in association with METHOTREXATE (Methotrexate). This represents 4.3% of all adverse event reports for METHOTREXATE.
10,973
Reports of Arthropathy with METHOTREXATE
4.3%
of all METHOTREXATE reports
1,648
Deaths
3,890
Hospitalizations
How Dangerous Is Arthropathy From METHOTREXATE?
Of the 10,973 reports, 1,648 (15.0%) resulted in death, 3,890 (35.5%) required hospitalization, and 2,205 (20.1%) were considered life-threatening.
Is Arthropathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 10,973 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Arthropathy?
ETANERCEPT (11,842)
ADALIMUMAB (11,670)
ABATACEPT (11,099)
TOCILIZUMAB (9,816)
LEFLUNOMIDE (9,277)
HYDROXYCHLOROQUINE (8,770)
RITUXIMAB (8,619)
INFLIXIMAB (8,410)
SULFASALAZINE (7,545)
PREDNISONE (7,257)
Which METHOTREXATE Alternatives Have Lower Arthropathy Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA