Does BUPIVACAINE Cause Malaise? 129 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 129 reports of Malaise have been filed in association with BUPIVACAINE (Bupivacaine Hydrochloride). This represents 1.1% of all adverse event reports for BUPIVACAINE.
129
Reports of Malaise with BUPIVACAINE
1.1%
of all BUPIVACAINE reports
10
Deaths
53
Hospitalizations
How Dangerous Is Malaise From BUPIVACAINE?
Of the 129 reports, 10 (7.8%) resulted in death, 53 (41.1%) required hospitalization, and 33 (25.6%) were considered life-threatening.
Is Malaise Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BUPIVACAINE. However, 129 reports have been filed with the FAERS database.
What Other Side Effects Does BUPIVACAINE Cause?
Drug ineffective (3,068)
Off label use (912)
Pain (746)
Anaesthetic complication (585)
Maternal exposure during pregnancy (491)
Hypotension (460)
Hypoaesthesia (455)
Exposure during pregnancy (391)
Nausea (328)
Drug withdrawal syndrome (280)
What Other Drugs Cause Malaise?
ADALIMUMAB (15,965)
ETANERCEPT (13,600)
METHOTREXATE (9,970)
TOFACITINIB (9,040)
SECUKINUMAB (8,570)
INFLIXIMAB (7,477)
RITUXIMAB (6,587)
PREGABALIN (6,320)
PREDNISONE (6,319)
ABATACEPT (6,251)
Which BUPIVACAINE Alternatives Have Lower Malaise Risk?
BUPIVACAINE vs BUPIVACAINE\BUPIVACAINE ANHYDROUS
BUPIVACAINE vs BUPIVACAINE\EPINEPHRINE
BUPIVACAINE vs BUPIVACAINE\MELOXICAM
BUPIVACAINE vs BUPRENORPHINE
BUPIVACAINE vs BUPRENORPHINE\NALOXONE