Does BUPRENORPHINE Cause Dependence? 3,184 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 3,184 reports of Dependence have been filed in association with BUPRENORPHINE (Buprenorphine and Naloxone). This represents 3.9% of all adverse event reports for BUPRENORPHINE.
3,184
Reports of Dependence with BUPRENORPHINE
3.9%
of all BUPRENORPHINE reports
341
Deaths
61
Hospitalizations
How Dangerous Is Dependence From BUPRENORPHINE?
Of the 3,184 reports, 341 (10.7%) resulted in death, 61 (1.9%) required hospitalization, and 9 (0.3%) were considered life-threatening.
Is Dependence Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BUPRENORPHINE. However, 3,184 reports have been filed with the FAERS database.
What Other Side Effects Does BUPRENORPHINE Cause?
Drug dependence (16,730)
Overdose (13,977)
Death (13,604)
Toxicity to various agents (10,906)
Pain (8,219)
Drug withdrawal syndrome (7,149)
Emotional distress (6,159)
Drug abuse (4,344)
Drug ineffective (4,261)
Product adhesion issue (3,158)
What Other Drugs Cause Dependence?
ACETAMINOPHEN\HYDROCODONE (28,841)
ACETAMINOPHEN\OXYCODONE (26,147)
OXYMORPHONE (8,816)
TRAMADOL (8,530)
MORPHINE (5,656)
FENTANYL (4,358)
ACETAMINOPHEN\CODEINE (3,857)
CODEINE\PROMETHAZINE (3,521)
HYDROCODONE\IBUPROFEN (3,304)
PROPOXYPHENE (3,206)
Which BUPRENORPHINE Alternatives Have Lower Dependence Risk?
BUPRENORPHINE vs BUPRENORPHINE\NALOXONE
BUPRENORPHINE vs BUPROPION
BUPRENORPHINE vs BUPROPION HYDROBROMIDE
BUPRENORPHINE vs BUPROPION\DEXTROMETHORPHAN HYDROBROMIDE
BUPRENORPHINE vs BUPROPION\NALTREXONE