Does BUPROPION Cause Serotonin syndrome? 1,058 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,058 reports of Serotonin syndrome have been filed in association with BUPROPION (Bupropion Hydrochloride (XL)). This represents 3.0% of all adverse event reports for BUPROPION.
1,058
Reports of Serotonin syndrome with BUPROPION
3.0%
of all BUPROPION reports
24
Deaths
799
Hospitalizations
How Dangerous Is Serotonin syndrome From BUPROPION?
Of the 1,058 reports, 24 (2.3%) resulted in death, 799 (75.5%) required hospitalization, and 199 (18.8%) were considered life-threatening.
Is Serotonin syndrome Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for BUPROPION. However, 1,058 reports have been filed with the FAERS database.
What Other Side Effects Does BUPROPION Cause?
Completed suicide (5,095)
Drug ineffective (3,991)
Toxicity to various agents (3,837)
Depression (2,486)
Overdose (2,357)
Headache (2,323)
Anxiety (2,145)
Intentional overdose (2,103)
Drug hypersensitivity (1,967)
Seizure (1,894)
What Other Drugs Cause Serotonin syndrome?
VENLAFAXINE (1,632)
SERTRALINE (1,563)
FLUOXETINE (1,457)
DULOXETINE (1,352)
TRAMADOL (1,229)
ESCITALOPRAM OXALATE (1,051)
QUETIAPINE (947)
TRAZODONE (831)
FENTANYL (778)
PAROXETINE (742)
Which BUPROPION Alternatives Have Lower Serotonin syndrome Risk?
BUPROPION vs BUPROPION HYDROBROMIDE
BUPROPION vs BUPROPION\DEXTROMETHORPHAN HYDROBROMIDE
BUPROPION vs BUPROPION\NALTREXONE
BUPROPION vs BUROSUMAB
BUPROPION vs BUROSUMAB-TWZA