BUSULFAN for Autologous haematopoietic stem cell transplant: Side Effects & Safety Data
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There are 240 adverse event reports in the FDA FAERS database where BUSULFAN was used for Autologous haematopoietic stem cell transplant.
Most Reported Side Effects for BUSULFAN
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 1,402 | 12.5% | 329 | 330 |
| Product use in unapproved indication | 1,387 | 12.3% | 250 | 119 |
| Mucosal inflammation | 880 | 7.8% | 156 | 238 |
| Venoocclusive liver disease | 765 | 6.8% | 250 | 190 |
| Febrile neutropenia | 628 | 5.6% | 103 | 218 |
| Cytomegalovirus infection | 620 | 5.5% | 197 | 122 |
| Drug ineffective | 569 | 5.1% | 127 | 163 |
| Graft versus host disease | 507 | 4.5% | 192 | 74 |
| Pyrexia | 502 | 4.5% | 135 | 245 |
| Cytomegalovirus infection reactivation | 481 | 4.3% | 87 | 76 |
| Sepsis | 421 | 3.7% | 290 | 102 |
| Thrombocytopenia | 376 | 3.3% | 55 | 136 |
| Respiratory failure | 360 | 3.2% | 266 | 162 |
| Infection | 357 | 3.2% | 267 | 28 |
| Pneumonia | 341 | 3.0% | 169 | 99 |
Other Indications for BUSULFAN
Bone marrow conditioning regimen (4,669)
Stem cell transplant (1,700)
Allogenic stem cell transplantation (1,624)
Acute myeloid leukaemia (892)
Product used for unknown indication (436)
Prophylaxis against transplant rejection (428)
Chemotherapy (267)
Neuroblastoma (252)
Prophylaxis against graft versus host disease (221)
Immunosuppressant drug therapy (194)
Other Drugs Used for Autologous haematopoietic stem cell transplant
MELPHALAN (284)
THIOTEPA (275)
FILGRASTIM (193)
ETOPOSIDE (151)
CYCLOPHOSPHAMIDE (135)
CYTARABINE (134)
CARBOPLATIN (81)
CARMUSTINE (78)
FLUDARABINE (43)
LENALIDOMIDE (41)