Does BUSULFAN Cause Graft versus host disease? 507 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 507 reports of Graft versus host disease have been filed in association with BUSULFAN (Busulfan). This represents 4.5% of all adverse event reports for BUSULFAN.
507
Reports of Graft versus host disease with BUSULFAN
4.5%
of all BUSULFAN reports
192
Deaths
74
Hospitalizations
How Dangerous Is Graft versus host disease From BUSULFAN?
Of the 507 reports, 192 (37.9%) resulted in death, 74 (14.6%) required hospitalization, and 24 (4.7%) were considered life-threatening.
Is Graft versus host disease Listed in the Official Label?
Yes, Graft versus host disease is listed as a known adverse reaction in the official FDA drug label for BUSULFAN.
What Other Side Effects Does BUSULFAN Cause?
Off label use (1,402)
Product use in unapproved indication (1,387)
Mucosal inflammation (880)
Venoocclusive liver disease (765)
Febrile neutropenia (628)
Cytomegalovirus infection (620)
Drug ineffective (569)
Pyrexia (502)
Cytomegalovirus infection reactivation (481)
Sepsis (421)
What Other Drugs Cause Graft versus host disease?
CYCLOSPORINE (1,131)
TACROLIMUS (900)
MYCOPHENOLATE MOFETIL (890)
CYCLOPHOSPHAMIDE (653)
METHOTREXATE (615)
FLUDARABINE (541)
RUXOLITINIB (469)
METHYLPREDNISOLONE (429)
PREDNISONE (405)
RITUXIMAB (238)
Which BUSULFAN Alternatives Have Lower Graft versus host disease Risk?
BUSULFAN vs BUSULFEX
BUSULFAN vs BUTALBITAL
BUSULFAN vs BUTENAFINE
BUSULFAN vs BUTORPHANOL
BUSULFAN vs BUTRANS