Graft versus host disease: Which Medications Cause It? (4,565 Reports Across 250 Drugs)
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Graft versus host disease has been reported as an adverse event with 250 different drugs in the FDA's FAERS database, with 4,565 total reports. 1,554 of these reports resulted in death.The drugs most commonly associated with Graft versus host disease are CYCLOSPORINE, TACROLIMUS, and MYCOPHENOLATE MOFETIL.
4,565
Total Reports
250
Drugs Involved
1,554
Deaths
1,192
Hospitalizations
39.8 yrs
Average Patient Age
40.5% / 59.5%
Female / Male
Which Drugs Cause Graft versus host disease Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| CYCLOSPORINE | 1,131 | 1.7% | 369 | 204 | 65 |
| TACROLIMUS | 900 | 1.0% | 317 | 218 | 57 |
| MYCOPHENOLATE MOFETIL | 890 | 1.2% | 338 | 181 | 44 |
| CYCLOPHOSPHAMIDE | 653 | 0.5% | 202 | 116 | 37 |
| METHOTREXATE | 615 | 0.2% | 192 | 124 | 26 |
| FLUDARABINE | 541 | 2.3% | 234 | 109 | 35 |
| BUSULFAN | 507 | 4.5% | 192 | 74 | 24 |
| RUXOLITINIB | 469 | 0.7% | 110 | 185 | 13 |
| METHYLPREDNISOLONE | 429 | 0.7% | 171 | 121 | 62 |
| PREDNISONE | 405 | 0.3% | 108 | 92 | 12 |
| RITUXIMAB | 238 | 0.1% | 80 | 31 | 6 |
| PREDNISOLONE | 223 | 0.3% | 79 | 47 | 33 |
| CYTARABINE | 219 | 0.5% | 70 | 64 | 18 |
| THIOTEPA | 204 | 3.0% | 110 | 29 | 4 |
| DEXAMETHASONE | 193 | 0.2% | 54 | 45 | 14 |
| MELPHALAN | 192 | 1.2% | 73 | 49 | 17 |
| LAPINE T-LYMPHOCYTE IMMUNE GLOBULIN | 191 | 2.1% | 80 | 52 | 31 |
| IMATINIB | 147 | 0.3% | 24 | 17 | 8 |
| SIROLIMUS | 144 | 1.3% | 68 | 40 | 5 |
| PONATINIB | 132 | 1.3% | 26 | 69 | 3 |