Does CLOFARABINE Cause Pancytopenia? 69 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 69 reports of Pancytopenia have been filed in association with CLOFARABINE (Clofarabine). This represents 4.9% of all adverse event reports for CLOFARABINE.
69
Reports of Pancytopenia with CLOFARABINE
4.9%
of all CLOFARABINE reports
27
Deaths
23
Hospitalizations
How Dangerous Is Pancytopenia From CLOFARABINE?
Of the 69 reports, 27 (39.1%) resulted in death, 23 (33.3%) required hospitalization, and 17 (24.6%) were considered life-threatening.
Is Pancytopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CLOFARABINE. However, 69 reports have been filed with the FAERS database.
What Other Side Effects Does CLOFARABINE Cause?
Febrile neutropenia (201)
Off label use (158)
Drug ineffective (139)
Pyrexia (139)
Mucosal inflammation (89)
Sepsis (85)
Alanine aminotransferase increased (82)
Acute kidney injury (80)
Multiple organ dysfunction syndrome (77)
Aspartate aminotransferase increased (76)
What Other Drugs Cause Pancytopenia?
METHOTREXATE (5,377)
CYCLOPHOSPHAMIDE (3,351)
CARBOPLATIN (2,910)
RITUXIMAB (2,400)
LENALIDOMIDE (2,259)
DOXORUBICIN (2,212)
VINCRISTINE (2,180)
ETOPOSIDE (2,129)
DEXAMETHASONE (2,053)
PREDNISONE (1,743)
Which CLOFARABINE Alternatives Have Lower Pancytopenia Risk?
CLOFARABINE vs CLOFAZIMINE
CLOFARABINE vs CLOMETHIAZOLE
CLOFARABINE vs CLOMIPHENE
CLOFARABINE vs CLOMIPRAMINE
CLOFARABINE vs CLONAZEPAM