COBIMETINIB for Transitional cell carcinoma: Side Effects & Safety Data
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There are 6 adverse event reports in the FDA FAERS database where COBIMETINIB was used for Transitional cell carcinoma.
Most Reported Side Effects for COBIMETINIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Diarrhoea | 412 | 10.1% | 39 | 214 |
| Off label use | 411 | 10.1% | 40 | 65 |
| Rash | 369 | 9.1% | 11 | 166 |
| Pyrexia | 332 | 8.2% | 19 | 228 |
| Death | 231 | 5.7% | 230 | 23 |
| Nausea | 206 | 5.1% | 17 | 105 |
| Fatigue | 198 | 4.9% | 15 | 93 |
| No adverse event | 178 | 4.4% | 0 | 1 |
| Vomiting | 168 | 4.1% | 20 | 108 |
| Acute kidney injury | 133 | 3.3% | 18 | 114 |
| Photosensitivity reaction | 124 | 3.1% | 10 | 44 |
| Asthenia | 119 | 2.9% | 13 | 68 |
| Rash maculo-papular | 118 | 2.9% | 7 | 73 |
| Blood creatine phosphokinase increased | 114 | 2.8% | 5 | 58 |
| Drug reaction with eosinophilia and systemic symptoms | 113 | 2.8% | 6 | 72 |
Other Indications for COBIMETINIB
Malignant melanoma (1,324)
Metastatic malignant melanoma (898)
Product used for unknown indication (402)
Histiocytosis (98)
Erdheim-chester disease (90)
Plasma cell myeloma (76)
Neoplasm malignant (70)
Neoplasm (68)
Langerhans' cell histiocytosis (56)
Cholangiocarcinoma (53)
Other Drugs Used for Transitional cell carcinoma
PEMBROLIZUMAB (1,951)
ENFORTUMAB VEDOTIN-EJFV (1,179)
GEMCITABINE (825)
ATEZOLIZUMAB (788)
CISPLATIN (672)
ENFORTUMAB VEDOTIN (649)
NIVOLUMAB (595)
AVELUMAB (554)
CARBOPLATIN (493)
GEMCITABINE\GEMCITABINE (255)