Does COBIMETINIB Cause Hepatic enzyme increased? 27 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 27 reports of Hepatic enzyme increased have been filed in association with COBIMETINIB (Cotellic). This represents 0.7% of all adverse event reports for COBIMETINIB.
27
Reports of Hepatic enzyme increased with COBIMETINIB
0.7%
of all COBIMETINIB reports
1
Deaths
12
Hospitalizations
How Dangerous Is Hepatic enzyme increased From COBIMETINIB?
Of the 27 reports, 1 (3.7%) resulted in death, 12 (44.4%) required hospitalization, and 2 (7.4%) were considered life-threatening.
Is Hepatic enzyme increased Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for COBIMETINIB. However, 27 reports have been filed with the FAERS database.
What Other Side Effects Does COBIMETINIB Cause?
Diarrhoea (412)
Off label use (411)
Rash (369)
Pyrexia (332)
Death (231)
Nausea (206)
Fatigue (198)
No adverse event (178)
Vomiting (168)
Acute kidney injury (133)
What Other Drugs Cause Hepatic enzyme increased?
METHOTREXATE (9,857)
ADALIMUMAB (8,693)
TOCILIZUMAB (7,691)
ETANERCEPT (7,481)
ABATACEPT (7,397)
RITUXIMAB (7,247)
LEFLUNOMIDE (7,173)
INFLIXIMAB (6,778)
HYDROXYCHLOROQUINE (6,555)
TOFACITINIB (6,269)
Which COBIMETINIB Alternatives Have Lower Hepatic enzyme increased Risk?
COBIMETINIB vs COCAETHYLENE
COBIMETINIB vs COCAINE
COBIMETINIB vs COCOA BUTTER\PHENYLEPHRINE
COBIMETINIB vs COD LIVER OIL
COBIMETINIB vs CODEINE