Does CODEINE Cause Bone erosion? 155 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 155 reports of Bone erosion have been filed in association with CODEINE (Codeine-Guaifenesin). This represents 0.7% of all adverse event reports for CODEINE.
155
Reports of Bone erosion with CODEINE
0.7%
of all CODEINE reports
136
Deaths
144
Hospitalizations
How Dangerous Is Bone erosion From CODEINE?
Of the 155 reports, 136 (87.7%) resulted in death, 144 (92.9%) required hospitalization, and 125 (80.6%) were considered life-threatening.
Is Bone erosion Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CODEINE. However, 155 reports have been filed with the FAERS database.
What Other Side Effects Does CODEINE Cause?
Drug hypersensitivity (7,479)
Toxicity to various agents (2,951)
Drug ineffective (2,632)
Drug abuse (2,122)
Pain (2,024)
Rash (1,931)
Nausea (1,907)
Rheumatoid arthritis (1,861)
Headache (1,701)
Off label use (1,662)
What Other Drugs Cause Bone erosion?
METHOTREXATE (1,713)
ADALIMUMAB (1,640)
ETANERCEPT (1,474)
TOCILIZUMAB (1,374)
LEFLUNOMIDE (1,291)
ABATACEPT (1,264)
HYDROXYCHLOROQUINE (1,138)
RITUXIMAB (1,064)
SULFASALAZINE (1,042)
INFLIXIMAB (1,040)
Which CODEINE Alternatives Have Lower Bone erosion Risk?
CODEINE vs CODEINE\GUAIFENESIN
CODEINE vs CODEINE\IBUPROFEN
CODEINE vs CODEINE\PROMETHAZINE
CODEINE vs COLCHICINE
CODEINE vs COLCHICINE\DICYCLOMINE