Does CODEINE Cause Dependence? 1,015 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,015 reports of Dependence have been filed in association with CODEINE (Codeine-Guaifenesin). This represents 4.6% of all adverse event reports for CODEINE.
1,015
Reports of Dependence with CODEINE
4.6%
of all CODEINE reports
51
Deaths
22
Hospitalizations
How Dangerous Is Dependence From CODEINE?
Of the 1,015 reports, 51 (5.0%) resulted in death, 22 (2.2%) required hospitalization, and 17 (1.7%) were considered life-threatening.
Is Dependence Listed in the Official Label?
Yes, Dependence is listed as a known adverse reaction in the official FDA drug label for CODEINE.
What Other Side Effects Does CODEINE Cause?
Drug hypersensitivity (7,479)
Toxicity to various agents (2,951)
Drug ineffective (2,632)
Drug abuse (2,122)
Pain (2,024)
Rash (1,931)
Nausea (1,907)
Rheumatoid arthritis (1,861)
Headache (1,701)
Off label use (1,662)
What Other Drugs Cause Dependence?
ACETAMINOPHEN\HYDROCODONE (28,841)
ACETAMINOPHEN\OXYCODONE (26,147)
OXYMORPHONE (8,816)
TRAMADOL (8,530)
MORPHINE (5,656)
FENTANYL (4,358)
ACETAMINOPHEN\CODEINE (3,857)
CODEINE\PROMETHAZINE (3,521)
HYDROCODONE\IBUPROFEN (3,304)
PROPOXYPHENE (3,206)
Which CODEINE Alternatives Have Lower Dependence Risk?
CODEINE vs CODEINE\GUAIFENESIN
CODEINE vs CODEINE\IBUPROFEN
CODEINE vs CODEINE\PROMETHAZINE
CODEINE vs COLCHICINE
CODEINE vs COLCHICINE\DICYCLOMINE