Does CRIZOTINIB Cause Cardiac failure? 104 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 104 reports of Cardiac failure have been filed in association with CRIZOTINIB (Xalkori). This represents 1.1% of all adverse event reports for CRIZOTINIB.
104
Reports of Cardiac failure with CRIZOTINIB
1.1%
of all CRIZOTINIB reports
31
Deaths
50
Hospitalizations
How Dangerous Is Cardiac failure From CRIZOTINIB?
Of the 104 reports, 31 (29.8%) resulted in death, 50 (48.1%) required hospitalization, and 12 (11.5%) were considered life-threatening.
Is Cardiac failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for CRIZOTINIB. However, 104 reports have been filed with the FAERS database.
What Other Side Effects Does CRIZOTINIB Cause?
Death (2,028)
Neoplasm progression (1,161)
Nausea (820)
Disease progression (677)
Diarrhoea (631)
Vomiting (600)
Fatigue (419)
Off label use (353)
Dyspnoea (352)
Visual impairment (315)
What Other Drugs Cause Cardiac failure?
SACUBITRIL\VALSARTAN (4,504)
FUROSEMIDE (1,841)
APIXABAN (1,575)
CYCLOPHOSPHAMIDE (1,514)
DOXORUBICIN (1,367)
ADALIMUMAB (1,278)
DEXAMETHASONE (1,271)
TREPROSTINIL (1,168)
BISOPROLOL (1,159)
LENALIDOMIDE (1,115)
Which CRIZOTINIB Alternatives Have Lower Cardiac failure Risk?
CRIZOTINIB vs CROFELEMER
CRIZOTINIB vs CROMOLYN
CRIZOTINIB vs CROTALIDAE POLYVALENT IMMUNE FAB
CRIZOTINIB vs CUBICIN
CRIZOTINIB vs CUPRIC