DABRAFENIB for Braf gene mutation: Side Effects & Safety Data
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There are 224 adverse event reports in the FDA FAERS database where DABRAFENIB was used for Braf gene mutation.
Most Reported Side Effects for DABRAFENIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Pyrexia | 3,788 | 19.6% | 352 | 1,599 |
| Death | 2,740 | 14.2% | 2,733 | 198 |
| Malignant neoplasm progression | 1,667 | 8.6% | 693 | 496 |
| Fatigue | 1,328 | 6.9% | 135 | 338 |
| Nausea | 1,300 | 6.7% | 178 | 450 |
| Chills | 1,235 | 6.4% | 90 | 419 |
| Rash | 1,078 | 5.6% | 82 | 244 |
| Vomiting | 907 | 4.7% | 122 | 445 |
| Diarrhoea | 901 | 4.7% | 103 | 357 |
| Headache | 697 | 3.6% | 69 | 228 |
| Asthenia | 667 | 3.5% | 124 | 289 |
| Malaise | 585 | 3.0% | 86 | 237 |
| Decreased appetite | 546 | 2.8% | 110 | 215 |
| Arthralgia | 539 | 2.8% | 40 | 146 |
| Product use in unapproved indication | 504 | 2.6% | 94 | 60 |
Other Indications for DABRAFENIB
Malignant melanoma (5,277)
Product used for unknown indication (4,430)
Metastatic malignant melanoma (3,885)
Lung neoplasm malignant (610)
Thyroid cancer (583)
Non-small cell lung cancer (557)
Neoplasm malignant (356)
Braf v600e mutation positive (213)
Malignant melanoma stage iv (197)
Brain neoplasm malignant (189)
Other Drugs Used for Braf gene mutation
TRAMETINIB DIMETHYL SULFOXIDE (129)
TRAMETINIB (94)
ENCORAFENIB (83)
BINIMETINIB (59)
VEMURAFENIB (34)
PREDNISOLONE (26)
VINBLASTINE (26)
CETUXIMAB (17)
COBIMETINIB (14)
PEMBROLIZUMAB (14)