VEMURAFENIB for Braf gene mutation: Side Effects & Safety Data
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There are 34 adverse event reports in the FDA FAERS database where VEMURAFENIB was used for Braf gene mutation.
Most Reported Side Effects for VEMURAFENIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Rash | 1,202 | 14.0% | 52 | 239 |
| Arthralgia | 783 | 9.2% | 27 | 79 |
| Off label use | 782 | 9.1% | 90 | 120 |
| Fatigue | 773 | 9.0% | 37 | 122 |
| Diarrhoea | 655 | 7.7% | 51 | 225 |
| Nausea | 601 | 7.0% | 46 | 137 |
| Pyrexia | 569 | 6.7% | 33 | 299 |
| Death | 505 | 5.9% | 504 | 37 |
| Alopecia | 445 | 5.2% | 8 | 32 |
| Decreased appetite | 383 | 4.5% | 22 | 79 |
| Vomiting | 342 | 4.0% | 36 | 141 |
| No adverse event | 341 | 4.0% | 3 | 2 |
| Photosensitivity reaction | 321 | 3.8% | 20 | 64 |
| Pruritus | 305 | 3.6% | 13 | 54 |
| Sunburn | 292 | 3.4% | 7 | 24 |
Other Indications for VEMURAFENIB
Malignant melanoma (2,548)
Product used for unknown indication (2,079)
Metastatic malignant melanoma (1,848)
Hairy cell leukaemia (236)
Neoplasm malignant (188)
Langerhans' cell histiocytosis (146)
Thyroid cancer (119)
Colon cancer (110)
Erdheim-chester disease (108)
Malignant melanoma stage iv (88)
Other Drugs Used for Braf gene mutation
DABRAFENIB (224)
TRAMETINIB DIMETHYL SULFOXIDE (129)
TRAMETINIB (94)
ENCORAFENIB (83)
BINIMETINIB (59)
PREDNISOLONE (26)
VINBLASTINE (26)
CETUXIMAB (17)
COBIMETINIB (14)
PEMBROLIZUMAB (14)