DACOMITINIB for Egfr gene mutation: Side Effects & Safety Data
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There are 6 adverse event reports in the FDA FAERS database where DACOMITINIB was used for Egfr gene mutation.
Most Reported Side Effects for DACOMITINIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Death | 253 | 37.1% | 253 | 18 |
| Diarrhoea | 114 | 16.7% | 23 | 36 |
| Rash | 108 | 15.8% | 22 | 17 |
| Neoplasm progression | 78 | 11.4% | 39 | 14 |
| Paronychia | 55 | 8.1% | 5 | 10 |
| Blood pressure increased | 47 | 6.9% | 9 | 7 |
| Off label use | 35 | 5.1% | 10 | 10 |
| Pruritus | 34 | 5.0% | 7 | 9 |
| Dyspnoea | 30 | 4.4% | 7 | 13 |
| Carcinoembryonic antigen increased | 28 | 4.1% | 5 | 2 |
| Pain | 28 | 4.1% | 4 | 7 |
| Decreased appetite | 27 | 4.0% | 13 | 8 |
| Malignant neoplasm progression | 26 | 3.8% | 11 | 6 |
| Vomiting | 26 | 3.8% | 10 | 9 |
| Asthenia | 24 | 3.5% | 6 | 8 |
Other Indications for DACOMITINIB
Non-small cell lung cancer (103)
Lung neoplasm malignant (76)
Lung adenocarcinoma (63)
Lung cancer metastatic (39)
Non-small cell lung cancer metastatic (36)
Lung adenocarcinoma stage iv (12)
Product used for unknown indication (10)
Non-small cell lung cancer stage iv (7)
Targeted cancer therapy (7)
Adenocarcinoma (6)
Other Drugs Used for Egfr gene mutation
AFATINIB (780)
OSIMERTINIB (695)
GEFITINIB (97)
AMIVANTAMAB-VMJW (89)
ERLOTINIB (52)
PEMETREXED (34)
CARBOPLATIN (30)
MOBOCERTINIB (26)
BEVACIZUMAB (25)
NINTEDANIB (24)