Does DAPSONE Cause Methaemoglobinaemia? 322 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 322 reports of Methaemoglobinaemia have been filed in association with DAPSONE (Dapsone). This represents 9.7% of all adverse event reports for DAPSONE.
322
Reports of Methaemoglobinaemia with DAPSONE
9.7%
of all DAPSONE reports
13
Deaths
242
Hospitalizations
How Dangerous Is Methaemoglobinaemia From DAPSONE?
Of the 322 reports, 13 (4.0%) resulted in death, 242 (75.2%) required hospitalization, and 48 (14.9%) were considered life-threatening.
Is Methaemoglobinaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DAPSONE. However, 322 reports have been filed with the FAERS database.
What Other Side Effects Does DAPSONE Cause?
Drug ineffective (673)
Off label use (506)
Drug reaction with eosinophilia and systemic symptoms (345)
Treatment failure (260)
Product use in unapproved indication (168)
Condition aggravated (166)
Pyrexia (156)
Drug ineffective for unapproved indication (134)
Anaemia (117)
Haemolytic anaemia (101)
What Other Drugs Cause Methaemoglobinaemia?
LIDOCAINE (221)
ACETAMINOPHEN (186)
BENZOCAINE (162)
RASBURICASE (92)
SULFAMETHOXAZOLE\TRIMETHOPRIM (86)
LIDOCAINE\PRILOCAINE (67)
PRIMAQUINE (56)
HYDROXYCHLOROQUINE (54)
MEROPENEM (46)
PHENAZOPYRIDINE (46)
Which DAPSONE Alternatives Have Lower Methaemoglobinaemia Risk?
DAPSONE vs DAPTOMYCIN
DAPSONE vs DARATUMUMAB
DAPSONE vs DARATUMUMAB\HYALURONIDASE-FIHJ
DAPSONE vs DARBEPOETIN ALFA
DAPSONE vs DARIDOREXANT