Does DARATUMUMAB Cause Cardiac failure? 431 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 431 reports of Cardiac failure have been filed in association with DARATUMUMAB (DARZALEX). This represents 1.6% of all adverse event reports for DARATUMUMAB.
431
Reports of Cardiac failure with DARATUMUMAB
1.6%
of all DARATUMUMAB reports
122
Deaths
274
Hospitalizations
How Dangerous Is Cardiac failure From DARATUMUMAB?
Of the 431 reports, 122 (28.3%) resulted in death, 274 (63.6%) required hospitalization, and 45 (10.4%) were considered life-threatening.
Is Cardiac failure Listed in the Official Label?
Yes, Cardiac failure is listed as a known adverse reaction in the official FDA drug label for DARATUMUMAB.
What Other Side Effects Does DARATUMUMAB Cause?
Plasma cell myeloma (2,980)
Infusion related reaction (2,557)
Off label use (2,494)
Pneumonia (1,450)
Neutropenia (1,351)
Drug ineffective (1,110)
Thrombocytopenia (1,089)
Death (1,088)
Pyrexia (1,032)
Dyspnoea (996)
What Other Drugs Cause Cardiac failure?
SACUBITRIL\VALSARTAN (4,504)
FUROSEMIDE (1,841)
APIXABAN (1,575)
CYCLOPHOSPHAMIDE (1,514)
DOXORUBICIN (1,367)
ADALIMUMAB (1,278)
DEXAMETHASONE (1,271)
TREPROSTINIL (1,168)
BISOPROLOL (1,159)
LENALIDOMIDE (1,115)
Which DARATUMUMAB Alternatives Have Lower Cardiac failure Risk?
DARATUMUMAB vs DARATUMUMAB\HYALURONIDASE-FIHJ
DARATUMUMAB vs DARBEPOETIN ALFA
DARATUMUMAB vs DARIDOREXANT
DARATUMUMAB vs DARIFENACIN HYDROBROMIDE
DARATUMUMAB vs DAROLUTAMIDE