Does DARATUMUMAB Cause Hyperthermia? 14 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 14 reports of Hyperthermia have been filed in association with DARATUMUMAB (DARZALEX). This represents 0.1% of all adverse event reports for DARATUMUMAB.
14
Reports of Hyperthermia with DARATUMUMAB
0.1%
of all DARATUMUMAB reports
1
Deaths
10
Hospitalizations
How Dangerous Is Hyperthermia From DARATUMUMAB?
Of the 14 reports, 1 (7.1%) resulted in death, 10 (71.4%) required hospitalization.
Is Hyperthermia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DARATUMUMAB. However, 14 reports have been filed with the FAERS database.
What Other Side Effects Does DARATUMUMAB Cause?
Plasma cell myeloma (2,980)
Infusion related reaction (2,557)
Off label use (2,494)
Pneumonia (1,450)
Neutropenia (1,351)
Drug ineffective (1,110)
Thrombocytopenia (1,089)
Death (1,088)
Pyrexia (1,032)
Dyspnoea (996)
What Other Drugs Cause Hyperthermia?
QUETIAPINE (265)
OLANZAPINE (210)
ACETAMINOPHEN (196)
OXALIPLATIN (195)
RISPERIDONE (166)
LAMOTRIGINE (156)
HALOPERIDOL (138)
CARBOPLATIN (129)
FLUOROURACIL (115)
SERTRALINE (109)
Which DARATUMUMAB Alternatives Have Lower Hyperthermia Risk?
DARATUMUMAB vs DARATUMUMAB\HYALURONIDASE-FIHJ
DARATUMUMAB vs DARBEPOETIN ALFA
DARATUMUMAB vs DARIDOREXANT
DARATUMUMAB vs DARIFENACIN HYDROBROMIDE
DARATUMUMAB vs DAROLUTAMIDE