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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Hyperthermia: Which Medications Cause It? (4,985 Reports Across 452 Drugs)

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Hyperthermia has been reported as an adverse event with 452 different drugs in the FDA's FAERS database, with 4,985 total reports. 707 of these reports resulted in death.The drugs most commonly associated with Hyperthermia are QUETIAPINE, OLANZAPINE, and ACETAMINOPHEN.

4,985
Total Reports
452
Drugs Involved
707
Deaths
3,351
Hospitalizations
50.7 yrs
Average Patient Age
48.0% / 52.0%
Female / Male

Which Drugs Cause Hyperthermia Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
QUETIAPINE 265 0.4% 54 175 79
OLANZAPINE 210 0.4% 59 143 53
ACETAMINOPHEN 196 0.1% 14 144 44
OXALIPLATIN 195 0.4% 1 133 22
RISPERIDONE 166 0.2% 31 126 44
LAMOTRIGINE 156 0.3% 25 111 29
HALOPERIDOL 138 0.9% 20 107 43
CARBOPLATIN 129 0.2% 5 110 9
FLUOROURACIL 115 0.2% 6 84 9
SERTRALINE 109 0.2% 40 87 53
ESCITALOPRAM OXALATE 107 0.4% 33 70 11
CLONAZEPAM 100 0.3% 6 84 47
CLOZAPINE 100 0.1% 18 60 19
PACLITAXEL 100 0.1% 5 87 3
ARIPIPRAZOLE 98 0.2% 17 64 24
VENLAFAXINE 94 0.2% 10 84 24
RITUXIMAB 92 0.1% 8 65 3
AMITRIPTYLINE 90 0.4% 1 89 31
CARBIDOPA\LEVODOPA 89 0.2% 22 70 2
LITHIUM 88 0.6% 13 59 22

View all 452 drugs →

Top 3 Drugs Associated With Hyperthermia

265 reports
210 reports
196 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)