Does DARATUMUMAB Cause Hyponatraemia? 94 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 94 reports of Hyponatraemia have been filed in association with DARATUMUMAB (DARZALEX). This represents 0.3% of all adverse event reports for DARATUMUMAB.
94
Reports of Hyponatraemia with DARATUMUMAB
0.3%
of all DARATUMUMAB reports
14
Deaths
58
Hospitalizations
How Dangerous Is Hyponatraemia From DARATUMUMAB?
Of the 94 reports, 14 (14.9%) resulted in death, 58 (61.7%) required hospitalization, and 11 (11.7%) were considered life-threatening.
Is Hyponatraemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DARATUMUMAB. However, 94 reports have been filed with the FAERS database.
What Other Side Effects Does DARATUMUMAB Cause?
Plasma cell myeloma (2,980)
Infusion related reaction (2,557)
Off label use (2,494)
Pneumonia (1,450)
Neutropenia (1,351)
Drug ineffective (1,110)
Thrombocytopenia (1,089)
Death (1,088)
Pyrexia (1,032)
Dyspnoea (996)
What Other Drugs Cause Hyponatraemia?
FUROSEMIDE (3,127)
HYDROCHLOROTHIAZIDE (2,138)
OMEPRAZOLE (1,635)
LANSOPRAZOLE (1,416)
SERTRALINE (1,332)
RAMIPRIL (1,178)
SPIRONOLACTONE (1,166)
PANTOPRAZOLE (1,134)
INDAPAMIDE (976)
AMLODIPINE (879)
Which DARATUMUMAB Alternatives Have Lower Hyponatraemia Risk?
DARATUMUMAB vs DARATUMUMAB\HYALURONIDASE-FIHJ
DARATUMUMAB vs DARBEPOETIN ALFA
DARATUMUMAB vs DARIDOREXANT
DARATUMUMAB vs DARIFENACIN HYDROBROMIDE
DARATUMUMAB vs DAROLUTAMIDE