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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Hyponatraemia: Which Medications Cause It? (38,279 Reports Across 1,324 Drugs)

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Hyponatraemia has been reported as an adverse event with 1,324 different drugs in the FDA's FAERS database, with 38,279 total reports. 3,407 of these reports resulted in death.The drugs most commonly associated with Hyponatraemia are FUROSEMIDE, HYDROCHLOROTHIAZIDE, and OMEPRAZOLE.

38,279
Total Reports
1,324
Drugs Involved
3,407
Deaths
29,222
Hospitalizations
67.4 yrs
Average Patient Age
59.4% / 40.6%
Female / Male

Which Drugs Cause Hyponatraemia Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
FUROSEMIDE 3,127 6.0% 157 2,621 230
HYDROCHLOROTHIAZIDE 2,138 10.2% 67 1,809 204
OMEPRAZOLE 1,635 1.9% 72 1,494 127
LANSOPRAZOLE 1,416 2.3% 320 1,106 163
SERTRALINE 1,332 2.2% 29 1,104 148
RAMIPRIL 1,178 3.6% 72 991 123
SPIRONOLACTONE 1,166 5.5% 72 975 126
PANTOPRAZOLE 1,134 1.4% 71 923 83
INDAPAMIDE 976 20.0% 8 871 102
AMLODIPINE 879 1.4% 104 723 144
NIVOLUMAB 828 0.9% 173 669 124
CARBOPLATIN 799 1.0% 91 555 109
CITALOPRAM HYDROBROMIDE 770 2.9% 28 624 34
CYCLOPHOSPHAMIDE 759 0.6% 94 509 133
ACETAMINOPHEN 740 0.5% 364 520 202
ESOMEPRAZOLE 740 1.0% 10 662 29
ESCITALOPRAM OXALATE 738 2.4% 31 618 106
MIRTAZAPINE 712 2.5% 41 595 53
OXCARBAZEPINE 708 6.6% 10 367 36
DESMOPRESSIN 686 17.6% 23 524 81

View all 1,324 drugs →

Top 3 Drugs Associated With Hyponatraemia

3,127 reports
2,138 reports
1,635 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)