Does NIVOLUMAB Cause Hyponatraemia? 828 Reports in FDA Database

Q: Does NIVOLUMAB cause Hyponatraemia?

828 reports of Hyponatraemia have been filed with the FDA for NIVOLUMAB, representing 0.9% of all NIVOLUMAB adverse event reports.

Q: How dangerous is Hyponatraemia from NIVOLUMAB?

Of 828 reports, 173 (20.9%) resulted in death and 669 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 828 reports of Hyponatraemia have been filed in association with NIVOLUMAB (OPDIVO). This represents 0.9% of all adverse event reports for NIVOLUMAB.

828

Reports of Hyponatraemia with NIVOLUMAB

0.9%

of all NIVOLUMAB reports

173

Deaths

669

Hospitalizations

How Dangerous Is Hyponatraemia From NIVOLUMAB?

Of the 828 reports, 173 (20.9%) resulted in death, 669 (80.8%) required hospitalization, and 124 (15.0%) were considered life-threatening.

Is Hyponatraemia Listed in the Official Label?

This adverse event is not currently listed in the official FDA drug label for NIVOLUMAB. However, 828 reports have been filed with the FAERS database.

What Other Side Effects Does NIVOLUMAB Cause?

Death (11,216) Malignant neoplasm progression (9,363) Off label use (5,208) Diarrhoea (4,692) Fatigue (3,709) Pyrexia (3,454) Intentional product use issue (3,297) Rash (2,816) Nausea (2,805) Decreased appetite (2,619)

What Other Drugs Cause Hyponatraemia?

FUROSEMIDE (3,127) HYDROCHLOROTHIAZIDE (2,138) OMEPRAZOLE (1,635) LANSOPRAZOLE (1,416) SERTRALINE (1,332) RAMIPRIL (1,178) SPIRONOLACTONE (1,166) PANTOPRAZOLE (1,134) INDAPAMIDE (976) AMLODIPINE (879)

Which NIVOLUMAB Alternatives Have Lower Hyponatraemia Risk?

NIVOLUMAB vs NIVOLUMAB\RELATLIMAB-RMBW NIVOLUMAB vs NIZATIDINE NIVOLUMAB vs NOMEGESTROL NIVOLUMAB vs NORDAZEPAM NIVOLUMAB vs NOREPINEPHRINE

NIVOLUMAB Full Profile All Hyponatraemia Reports All Drugs Causing Hyponatraemia NIVOLUMAB Demographics