Does DARATUMUMAB Cause Myelosuppression? 471 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 471 reports of Myelosuppression have been filed in association with DARATUMUMAB (DARZALEX). This represents 1.7% of all adverse event reports for DARATUMUMAB.
471
Reports of Myelosuppression with DARATUMUMAB
1.7%
of all DARATUMUMAB reports
18
Deaths
166
Hospitalizations
How Dangerous Is Myelosuppression From DARATUMUMAB?
Of the 471 reports, 18 (3.8%) resulted in death, 166 (35.2%) required hospitalization, and 38 (8.1%) were considered life-threatening.
Is Myelosuppression Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DARATUMUMAB. However, 471 reports have been filed with the FAERS database.
What Other Side Effects Does DARATUMUMAB Cause?
Plasma cell myeloma (2,980)
Infusion related reaction (2,557)
Off label use (2,494)
Pneumonia (1,450)
Neutropenia (1,351)
Drug ineffective (1,110)
Thrombocytopenia (1,089)
Death (1,088)
Pyrexia (1,032)
Dyspnoea (996)
What Other Drugs Cause Myelosuppression?
CYCLOPHOSPHAMIDE (3,603)
CARBOPLATIN (2,624)
TRASTUZUMAB (2,552)
PACLITAXEL (2,522)
TISLELIZUMAB (2,142)
CYTARABINE (1,869)
VENETOCLAX (1,864)
CISPLATIN (1,849)
BEVACIZUMAB (1,744)
SODIUM (1,696)
Which DARATUMUMAB Alternatives Have Lower Myelosuppression Risk?
DARATUMUMAB vs DARATUMUMAB\HYALURONIDASE-FIHJ
DARATUMUMAB vs DARBEPOETIN ALFA
DARATUMUMAB vs DARIDOREXANT
DARATUMUMAB vs DARIFENACIN HYDROBROMIDE
DARATUMUMAB vs DAROLUTAMIDE