Myelosuppression: Which Medications Cause It? (27,095 Reports Across 477 Drugs)
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Myelosuppression has been reported as an adverse event with 477 different drugs in the FDA's FAERS database, with 27,095 total reports. 1,471 of these reports resulted in death.The drugs most commonly associated with Myelosuppression are CYCLOPHOSPHAMIDE, CARBOPLATIN, and TRASTUZUMAB.
27,095
Total Reports
477
Drugs Involved
1,471
Deaths
12,061
Hospitalizations
54.1 yrs
Average Patient Age
60.3% / 39.7%
Female / Male
Which Drugs Cause Myelosuppression Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| CYCLOPHOSPHAMIDE | 3,603 | 2.8% | 209 | 1,796 | 344 |
| CARBOPLATIN | 2,624 | 3.1% | 102 | 1,296 | 224 |
| TRASTUZUMAB | 2,552 | 5.5% | 10 | 1,110 | 86 |
| PACLITAXEL | 2,522 | 3.3% | 48 | 1,127 | 167 |
| TISLELIZUMAB | 2,142 | 42.9% | 5 | 1,052 | 91 |
| CYTARABINE | 1,869 | 4.2% | 107 | 1,017 | 332 |
| VENETOCLAX | 1,864 | 3.5% | 84 | 756 | 137 |
| CISPLATIN | 1,849 | 3.9% | 106 | 843 | 220 |
| BEVACIZUMAB | 1,744 | 2.2% | 48 | 597 | 112 |
| SODIUM | 1,696 | 7.3% | 5 | 937 | 113 |
| METHOTREXATE | 1,523 | 0.6% | 220 | 903 | 329 |
| RITUXIMAB | 1,436 | 0.8% | 179 | 647 | 179 |
| ETOPOSIDE | 1,394 | 2.7% | 106 | 628 | 180 |
| DOCETAXEL | 1,353 | 2.1% | 22 | 708 | 93 |
| PERTUZUMAB | 1,311 | 6.0% | 3 | 637 | 56 |
| VINCRISTINE | 1,280 | 1.8% | 117 | 618 | 160 |
| OXALIPLATIN | 1,257 | 2.2% | 44 | 492 | 112 |
| GEMCITABINE | 1,197 | 3.8% | 50 | 559 | 210 |
| DOXORUBICIN | 1,133 | 1.4% | 133 | 480 | 147 |
| DEXAMETHASONE | 1,030 | 0.8% | 120 | 369 | 105 |