Does DECITABINE Cause Pancytopenia? 88 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 88 reports of Pancytopenia have been filed in association with DECITABINE (Decitabine). This represents 3.0% of all adverse event reports for DECITABINE.
88
Reports of Pancytopenia with DECITABINE
3.0%
of all DECITABINE reports
21
Deaths
60
Hospitalizations
How Dangerous Is Pancytopenia From DECITABINE?
Of the 88 reports, 21 (23.9%) resulted in death, 60 (68.2%) required hospitalization, and 11 (12.5%) were considered life-threatening.
Is Pancytopenia Listed in the Official Label?
Yes, Pancytopenia is listed as a known adverse reaction in the official FDA drug label for DECITABINE.
What Other Side Effects Does DECITABINE Cause?
Febrile neutropenia (336)
Off label use (292)
Drug ineffective (253)
Pneumonia (243)
Myelosuppression (233)
Product use in unapproved indication (195)
Neutropenia (193)
Sepsis (175)
Acute myeloid leukaemia (172)
Thrombocytopenia (170)
What Other Drugs Cause Pancytopenia?
METHOTREXATE (5,377)
CYCLOPHOSPHAMIDE (3,351)
CARBOPLATIN (2,910)
RITUXIMAB (2,400)
LENALIDOMIDE (2,259)
DOXORUBICIN (2,212)
VINCRISTINE (2,180)
ETOPOSIDE (2,129)
DEXAMETHASONE (2,053)
PREDNISONE (1,743)
Which DECITABINE Alternatives Have Lower Pancytopenia Risk?
DECITABINE vs DEFERASIROX
DECITABINE vs DEFERIPRONE
DECITABINE vs DEFEROXAMINE
DECITABINE vs DEFIBROTIDE
DECITABINE vs DEFLAZACORT