Does DECITABINE Cause Second primary malignancy? 5 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 5 reports of Second primary malignancy have been filed in association with DECITABINE (Decitabine). This represents 0.2% of all adverse event reports for DECITABINE.
5
Reports of Second primary malignancy with DECITABINE
0.2%
of all DECITABINE reports
4
Deaths
2
Hospitalizations
How Dangerous Is Second primary malignancy From DECITABINE?
Of the 5 reports, 4 (80.0%) resulted in death, 2 (40.0%) required hospitalization, and 1 (20.0%) were considered life-threatening.
Is Second primary malignancy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DECITABINE. However, 5 reports have been filed with the FAERS database.
What Other Side Effects Does DECITABINE Cause?
Febrile neutropenia (336)
Off label use (292)
Drug ineffective (253)
Pneumonia (243)
Myelosuppression (233)
Product use in unapproved indication (195)
Neutropenia (193)
Sepsis (175)
Acute myeloid leukaemia (172)
Thrombocytopenia (170)
What Other Drugs Cause Second primary malignancy?
CYCLOPHOSPHAMIDE (1,247)
DOXORUBICIN (1,151)
VINCRISTINE (908)
IMATINIB (763)
PALBOCICLIB (658)
RITUXIMAB (646)
RUXOLITINIB (611)
ETOPOSIDE (573)
PREDNISONE (517)
OCTREOTIDE (496)
Which DECITABINE Alternatives Have Lower Second primary malignancy Risk?
DECITABINE vs DEFERASIROX
DECITABINE vs DEFERIPRONE
DECITABINE vs DEFEROXAMINE
DECITABINE vs DEFIBROTIDE
DECITABINE vs DEFLAZACORT