Does DEFERASIROX Cause Nephrolithiasis? 137 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 137 reports of Nephrolithiasis have been filed in association with DEFERASIROX (Deferasirox). This represents 1.2% of all adverse event reports for DEFERASIROX.
137
Reports of Nephrolithiasis with DEFERASIROX
1.2%
of all DEFERASIROX reports
6
Deaths
52
Hospitalizations
How Dangerous Is Nephrolithiasis From DEFERASIROX?
Of the 137 reports, 6 (4.4%) resulted in death, 52 (38.0%) required hospitalization, and 12 (8.8%) were considered life-threatening.
Is Nephrolithiasis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DEFERASIROX. However, 137 reports have been filed with the FAERS database.
What Other Side Effects Does DEFERASIROX Cause?
Death (1,583)
Diarrhoea (993)
Serum ferritin increased (732)
Haemoglobin decreased (615)
Pyrexia (607)
Malaise (605)
Nausea (603)
Sickle cell anaemia with crisis (570)
Vomiting (520)
Pneumonia (494)
What Other Drugs Cause Nephrolithiasis?
ADALIMUMAB (2,416)
ETANERCEPT (1,292)
INFLIXIMAB (981)
METHOTREXATE (979)
ABATACEPT (788)
TOPIRAMATE (768)
CERTOLIZUMAB PEGOL (735)
RITUXIMAB (709)
TOFACITINIB (699)
SODIUM OXYBATE (698)
Which DEFERASIROX Alternatives Have Lower Nephrolithiasis Risk?
DEFERASIROX vs DEFERIPRONE
DEFERASIROX vs DEFEROXAMINE
DEFERASIROX vs DEFIBROTIDE
DEFERASIROX vs DEFLAZACORT
DEFERASIROX vs DEGARELIX