Does DEFIBROTIDE Cause Underdose? 23 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 23 reports of Underdose have been filed in association with DEFIBROTIDE (DEFITELIO). This represents 0.6% of all adverse event reports for DEFIBROTIDE.
23
Reports of Underdose with DEFIBROTIDE
0.6%
of all DEFIBROTIDE reports
12
Deaths
10
Hospitalizations
How Dangerous Is Underdose From DEFIBROTIDE?
Of the 23 reports, 12 (52.2%) resulted in death, 10 (43.5%) required hospitalization, and 2 (8.7%) were considered life-threatening.
Is Underdose Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DEFIBROTIDE. However, 23 reports have been filed with the FAERS database.
What Other Side Effects Does DEFIBROTIDE Cause?
Off label use (1,323)
Venoocclusive disease (576)
Death (463)
Multiple organ dysfunction syndrome (372)
Venoocclusive liver disease (355)
Intentional product use issue (201)
Hypotension (169)
Haemorrhage (156)
Sepsis (143)
Acute graft versus host disease (140)
What Other Drugs Cause Underdose?
ADAPALENE (5,192)
AVOBENZONE\OCTISALATE\OCTOCRYLENE (3,722)
INSULIN LISPRO (3,156)
ETANERCEPT (3,145)
GALCANEZUMAB-GNLM (2,909)
ENZALUTAMIDE (2,017)
FLUTICASONE\SALMETEROL (1,600)
ALBUTEROL (1,593)
EXENATIDE (1,571)
TROFINETIDE (1,540)
Which DEFIBROTIDE Alternatives Have Lower Underdose Risk?
DEFIBROTIDE vs DEFLAZACORT
DEFIBROTIDE vs DEGARELIX
DEFIBROTIDE vs DELAFLOXACIN MEGLUMINE
DEFIBROTIDE vs DELAMANID
DEFIBROTIDE vs DELANDISTROGENE MOXEPARVOVEC-ROKL