Does DENOSUMAB Cause Bone loss? 441 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 441 reports of Bone loss have been filed in association with DENOSUMAB (Bilprevda). This represents 0.3% of all adverse event reports for DENOSUMAB.
441
Reports of Bone loss with DENOSUMAB
0.3%
of all DENOSUMAB reports
2
Deaths
33
Hospitalizations
How Dangerous Is Bone loss From DENOSUMAB?
Of the 441 reports, 2 (0.5%) resulted in death, 33 (7.5%) required hospitalization.
Is Bone loss Listed in the Official Label?
Yes, Bone loss is listed as a known adverse reaction in the official FDA drug label for DENOSUMAB.
What Other Side Effects Does DENOSUMAB Cause?
Off label use (34,612)
Death (16,545)
Osteonecrosis of jaw (8,438)
Arthralgia (5,890)
Pain in extremity (4,541)
Back pain (4,465)
Pain (4,102)
Product storage error (3,621)
Fall (3,322)
Fatigue (3,009)
What Other Drugs Cause Bone loss?
EMTRICITABINE\TENOFOVIR DISOPROXIL (8,967)
TENOFOVIR DISOPROXIL (7,040)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (4,493)
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL (2,114)
EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL (1,530)
ADALIMUMAB (189)
TERIPARATIDE (146)
ZOLEDRONIC ACID (122)
ALENDRONATE (98)
LOPINAVIR\RITONAVIR (95)
Which DENOSUMAB Alternatives Have Lower Bone loss Risk?
DENOSUMAB vs DEOXYCHOLIC ACID
DENOSUMAB vs DEPAKINE CHRONO
DENOSUMAB vs DEPAKOTE
DENOSUMAB vs DEPO-PROVERA
DENOSUMAB vs DERMATOPHAGOIDES FARINAE