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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Bone loss: Which Medications Cause It? (14,058 Reports Across 163 Drugs)

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Bone loss has been reported as an adverse event with 163 different drugs in the FDA's FAERS database, with 14,058 total reports. 192 of these reports resulted in death.The drugs most commonly associated with Bone loss are EMTRICITABINE\TENOFOVIR DISOPROXIL, TENOFOVIR DISOPROXIL, and EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL.

14,058
Total Reports
163
Drugs Involved
192
Deaths
1,054
Hospitalizations
50.0 yrs
Average Patient Age
36.9% / 63.1%
Female / Male

Which Drugs Cause Bone loss Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
EMTRICITABINE\TENOFOVIR DISOPROXIL 8,967 22.8% 113 469 0
TENOFOVIR DISOPROXIL 7,040 26.1% 107 382 0
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL 4,493 24.2% 41 234 0
COBICISTAT\ELVITEGRAVIR\EMTRICITABINE\TENOFOVIR DISOPROXIL 2,114 25.1% 20 102 0
EMTRICITABINE\RILPIVIRINE\TENOFOVIR DISOPROXIL 1,530 21.2% 20 74 0
DENOSUMAB 441 0.3% 2 33 0
ADALIMUMAB 189 0.0% 1 56 0
TERIPARATIDE 146 0.2% 0 4 0
ZOLEDRONIC ACID 122 0.4% 12 21 4
ALENDRONATE 98 0.4% 14 47 2
LOPINAVIR\RITONAVIR 95 1.2% 1 11 0
ETANERCEPT 88 0.0% 0 8 0
PREDNISONE 85 0.1% 0 26 0
METHOTREXATE 70 0.0% 0 21 0
IBANDRONATE 56 0.6% 0 8 0
LENALIDOMIDE 54 0.0% 0 4 0
ZOMETA 53 6.1% 17 39 0
RITUXIMAB 51 0.0% 1 12 0
ESOMEPRAZOLE 48 0.1% 0 5 1
LEUPROLIDE 46 0.1% 2 9 2

View all 163 drugs →

Top 3 Drugs Associated With Bone loss

7,040 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)